She was born around 2511 and was abducted by ONI to become a SPARTAN-II. She soon met Jai-006 while he was sneaking out. She gave him a paper clip she stole hidden under her tongue, in which their friendship began. She would constantly escape with Jai, but later would be captured by her trainers. She attempted these escapes with Jai not to escape but as an act of rebellion against her instructors. It was for her that SPARTAN-006 decided to stay with the program. Upon returning to base after their final escape attempt, she met a Spartan named Mike. Together, these Spartans would come together to form Gray Team.
Battle of the Rubble
Main article: Battle of the Rubble
Adriana and the other members of Gray Team are sent behind enemy lines in order to destroy the nav data held by the survivors of Madrigal, a world that had been glassed not long after Harvest. Also, along with then-Lieutenant Jacob Keyes and Ignatio Delgado, she helped save over a million refugees of Madrigal, some of which were Insurrectionists. After the events at the "Rubble", she was assigned with the rest of Gray Team to a mission even farther behind enemy lines. She was the first SPARTAN-II soldier to help Ignatio Delgado.
It has not been determined whether she survived to the end of the war. However, Frederic-104 mentioned Gray Team to be missing since 2551.
Adriana is unlike most of the other SPARTAN-IIs. Where most of the other Spartans adhere strictly to protocol and the chain of command, she does not. She is not above openly questioning her commanding officer or even contemplating taking a UNSC Prowler without clearance. Also, she seems to not mind being out of her armor, where as most other Spartans say that they feel exposed when they are not in their armor. She was partially responsible for neutralizing a situation that would have led to a massive violation of the Cole Protocol.